The UC Davis Department of Emergency Medicine has served the medical center and surrounding community since 1973. Prior to 1990, the Department's primary focus was the education of medical students/residents and patient care. However, over the past eighteen years the Department of Emergency Medicine has increasingly contributed to the growing body of medical research in the field of emergency medicine.

Recent grants that have been awarded to the Department of Emergency Medicine include awards of $2.4 million for a pediatric emergency medicine network (PECARN), $3.7 million to study the causes, consequences and prevention of violence, and $745,000 to study brain injury in older adults taking anticoagulants. Another $16 million worth of grants is pending review.

As the number of publications has increased, so has the breadth of research topics. This sharp increase in the number of publications clearly illustrates the intensifying faculty interest in conducting research.  

Status Epilepicus (SE) is a seizure lasting longer than five minutes without stopping on its own or without waking up.  A person whose seizure does not stop despite receiving a full dose of medicine (benzodiazepines) to make it stop is considered to have Established Status Epilepticus (ESE).
ESETT is a research study designed to try to save and improve the lives of people who experience established status epilepticus (ESE).  Emergency department care of patients with a long-lasting seizure in the US is not the same everywhere.  Doctors use their judgement, but what treatment will work best is not known.  This study plans to look at three commonly used medicines given in the emergency departments for ESE: fosphenytoin (fPHT), valproic acid (VPA), and levetiracetam (LVT) to learn which treatment is most effective at stopping a seizure quickly.

Normally, researchers get permission before a person can be included in a study.  A person having a seizure will not be able to give consent. Since a seizure that will not stop on its own must be treated quickly, there will not be enough time to locate and talk to the person’s legal representative about the study, so the person will be enrolled in the study without his/her legal representative’s consent.  This is called “Exception from Informed Consent” (EFIC). 

If you would like more information about the study or would like to decline participation, please go to our website or contact us by e-mail or phone. We would be happy to answer questions you have.

Local E.S.E.T.T. Contact Information

UC Davis Medical Center

Phone: 916-734-8847/ E-mail:

The UC Davis Violence Prevention Research Program (VPRP) is a multi-disciplinary program of research and policy development focused on the causes, consequences, and prevention of violence. Learn more about the Violence Prevention Research Program

Education Programs

The UC Davis Department of Emergency Medicine offers a two-year Emergency Medicine Research Fellowship. The program combines training in clinical emergency medicine research with graduate level training at UC Davis leading to either a Masters of Science in Clinical Epidemiology or Masters in Public Health.

The Department of Emergency Medicine can always use additional help with its research projects. If you are interested in learning more about emergency medicine research opportunities for undergraduate students, medical students, or residents, please contact the the research director Dr. James Holmes for more information. Undergraduates can learn more about our unique Emergency Medicine Research Assistant Program (EMRAP) here.

The emergency department has multiple research projects and many areas of research interests. Current research projects include:

General Emergency Medicine

  • Computational modeling of emergency services
  • Video-assisted laryngoscopy in emergencies
  • Ventilator asynchrony in critically ill or injured patients
  • Early treatments for patients with septic shock
  • TXA for non-traumatic hemorrhage
  • Coagulation studies for new oral anticoagulants
  • Methods to improved ED flow

Adult trauma

  • Airway management in patients with traumatic brain injury
  • Sedation monitoring in patients with traumatic brain injury
  • Biomarkers for traumatic brain injury
  • Prehospital guidelines for anticoagulated trauma patients

Pediatric Trauma

  • Utility of the FAST examination in children with blunt torso trauma
  • Implementation of a neuroimaging decision rule for childhood head trauma
  • TXA for Pediatric trauma

Pediatric Emergency Medicine

  • Cerebral edema in pediatric diabetic ketoacidosis
  • Improving the care of acutely ill and injured children in rural emergency departments with telemedicine
  • Biosignatures in young febrile infants
  • Medications for seizures

Emergency Department Epidemiology

  • Emergency department frequent users: community solutions
  • Use of firearms in youth suicides
  • Case control study of firearms retailers in California
  • Gun Violence in California
  • Impact of ambulance diversion on resident education study
  • Can patient centered outcome measures be used to predict length of stay? 

Infectious Diseases

  • Early detection of pathogens at triage
  • Antibiotic stewardship in the ED
  • Identification of rhinovirus via novel methods
  • Ultrasound for peritonsillar abscess


  • Cardiac resuscitation at STEMI versus non-STEMI centers
  • Gender differences in acute coronary syndrome
  • PET scan for cardiac risk stratification