Research Overview
Faculty Research Interests
Donald M. Bers, Ph.D.: Cardiac muscle electrophysiology, calcium dynamics and contractile regulation: Molecules to Heart.
Julie Bossuyt, D.V.M., Ph.D.: Cellular and molecular mechanisms of cardiac plasticity and disease.
Chao-Yin Chen, Ph.D.: Central neuroplasticity in cardiovascular regulation.
Ye Chen-Izu, Ph.D.: Cellular and molecular mechanisms of heart disease and biophysics of the cardiac muscle excitation, contraction coupling.
Yi-Je (Jay) Chen, D.V.M., Ph.D.: Potassium channels in ischemic stroke and neuroinflammation.
Nipavan Chiamvimonvat, M.D.: Functional roles of different isoforms of cardiac calcium channels using combined techniques of transgenic mouse models, gene silencing and patch-clamp recordings.
Colleen E. Clancy, Ph.D.: Computational approaches to reveal mechanisms of excitability in the heart and brain.
Elva Diaz, Ph.D.: Functional genomics of nervous system development.
Angela Gelli Ph.D.: Virulence determinants of fungal pathogenesis.
Eleonora Grandi, Ph.D.: Cellular mechanisms of complex cardiac arrhythmia diseases, such as heart failure and atrial fibrillation.
Johannes Hell Ph.D.: Molecular basis of synaptic plasticity and the role of signaling complexes.
Mary C. Horne, Ph.D.: Unconventional cyclin function during cellular growth, differentiation and stress responses.
Richard Horuk, Ph.D.: Chemokine receptors as therapeutic targets both for autoimmunity and for the treatment of malaria.
Leighton Izu, Ph.D.: Dynamics and stability of the cardiac control system.
Anne Knowlton, Ph.D.: Understanding the role of protein localization and post-translational modification of heat shock proteins (HSPs) and the estrogen receptor in cardiovascular disease.
Manuel Navedo, Ph.D.: Mechanisms of excitation - contraction and excitation - transcription coupling in arterial myocytes.
Crystal Ripplinger, Ph.D.: Mechanisms of cardiac arrhythmias; cardiovascular molecular imaging.
Michael A. Rogawski, M.D., Ph.D.: Cellular neurophysiology of ion channels; neurological therapeutics, with an emphasis on antiepileptic drugs and other epilepsy treatment approaches; treatment of traumatic brain injury and post-traumatic epilepsy.
Daisuke Sato, Ph.D.: Mathematical modeling of action potential and calcium cycling. Nonlinear dynamics of cardiac phenomena including alternans, early and delayed afterdepolarizations, Ca sparks, Ca waves.
David Segal, Ph.D.: Engineering zinc finger DNA-binding proteins for diagnostics and gene therapy.
Heike Wulff, Ph.D.: Potassium channel modulators for the treatment of autoimmune and cardiovascular disease.
Yang K. Xiang, Ph.D.: Neurohormonal regulation of GPCR signaling in heart failure and Alzheimer's diseases.