Congenital Adrenal Hyperplasia
Congenital adrenal hyperplasia (CAH) is a genetic condition that is present from birth. In people with classic CAH, the adrenal glands cannot make essential hormones called cortisol and aldosterone, and instead make too much of several male-type hormones called androgens. In girls with CAH this can lead to more male-like genitalia. Treatment for CAH requires taking medications that replace the missing cortisol and aldosterone, and missing these medications can be life-threatening. Growth and pubertal development also need to be closely monitored in children with CAH, as these processes can be affected by under- or over-treatment.